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Iron is an essential micronutrient required for the growth and development of all organisms. It is the second most abundant transition metal in the human body. Iron is mainly stored in ferritin, a highly conserved molecule found in a diverse range of organisms ([@b1-tr-34-161]). Ferritin is composed of 24 subunits of the same H and L ferritin subunits and exhibits a spherical protein shell that varies in size and number of iron deposits. Although the physiological function of ferritin is still under investigation, it is reported to serve as an iron storage protein, iron buffering protein, and mediator of iron-induced cell death ([@b2-tr-34-161]). Deregulation of iron homeostasis is one of the most common causes of iron overload in humans. It is considered a major cause of body iron storage and accumulation. Consistent with this, it is reported that iron overload significantly increases the expression of ferritin in the hepatic cells in humans and rodents ([@b3-tr-34-161]–[@b6-tr-34-161]).
Leucocytozoon is a sub-genus of protozoan with a complex life cycle involving a series of morphological changes, survival within a wide spectrum of intermediate hosts, and ingestion by the final definitive host ([@b7-tr-34-161],[@b8-tr-34-161]). Indirectly, the presence of iron in the diet causes severe iron deficiency and results in accumulation of iron, mainly in the liver, spleen, and lymphoid organs ([@b9-tr-34-161]–[@b11-tr-34-161]). Iron accumulation is also related to infectious diseases such as malaria and Babesia, which are caused by similar parasite species. Therefore, the current study was conducted to determine the effect of *Leuc
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